Detection of THC Use in Drivers

Proposal title: Detection of THC Use in Drivers The overall objective of this program is to develop a portable, cost-effective and non-invasive sensor device for near real-time salivary THC detection to be used at roadside in drivers. This will eliminate the need for expensive and time-consuming analytical techniques which have a turn-around time of several days. During the Phase I program Giner has successfully established a new methodology for THC measurement using disposable screen-printed electrodes. The performance of the sensor was tested in both controlled solution and in human saliva at physiologically relevant levels. The selectivity of the sensor and lack of false positive responses were successfully evaluated in the presence of potential interfering species. Phase II will include continued algorithm optimization, prototype development, and extensive saliva testing from clinical administration to human subjects in collaboration with an addiction research marijuana lab.